Major Crash detectives are working to understand why a van left a regional WA road and struck a tree, critically injuring two people.
A White Toyota HiAce van was travelling north on Wickepin-Corrigin Rd in Kunjin, 200km southeast of Perth, when the crash unfolded just before 6pm on Wednesday.
Two passengers, a 25-year-old woman and 36-year-old man, were critically injured and both were rushed to hospital, where they remain.
The driver and a third passenger managed to escape serious injury.
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Detectives are hoping witnesses who saw the van before the crash can supply information or mobile phone and dashcam vision to assist their investigation.
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